The Applied Genomics Centre
For infectious diseases. Genomics, lab work and data science for tuberculosis, malaria, vectors and antimicrobial resistance.
What we do
We are an interdisciplinary group working to understand infectious diseases, with a focus on tuberculosis, malaria and antimicrobial-resistant (AMR) infections. We combine 'omics, laboratory experiments and big data science to inform decisions in public health, clinical practice and surveillance.
We also help build genomic capacity in endemic settings. Through collaborative projects and hands-on workshops in 'omics and bioinformatics, we train researchers and healthcare professionals and grow a network that strengthens our shared response to infectious disease.
Latest news
All news-
Malaria Genomics Workshop at Mount Kenya University, November 4–6
As part of a symposium on malaria in pregnancy, organised by Mount Kenya University (MKU) through a Wellcome-funded project, the LSHTM team, led by Nina Billows, delivered a workshop on malaria genomics.
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The team travels to the ESOVE conference in Valencia
The team visited Valencia this week to talk about their work in the vector world such as the work on mosquito plant feeding or sandfly and tick research. Our own Emma even presented her work at the conference to showcase what we do at the school.
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New TB-Profiler version published in Genome Medicine
TB-Profiler has been expanded to support resistance profiling for 17 anti-TB drugs, including delamanid and pretomanid, using WHO-endorsed interpretation rules and curated loss-of-function mutations. A continuously expanding global database of over 170,000 M. tuberculosis isolates from 136 countries enables population-contextualised allele frequency comparisons and genomic relatedness analyses. Multilingual reporting further enhances the platform’s utility for clinical decision-making and genomic surveillance. The software is available from https://tbdr.lshtm.ac.uk/
Where we sit
PathogenSeq is part of the Faculty of Infectious and Tropical Diseases at the London School of Hygiene & Tropical Medicine. The Faculty is home to the School's laboratory-based research, alongside clinical and epidemiological work on infectious and tropical diseases.
LSHTM is a specialist postgraduate university for public and global health, founded in 1899 and based in Bloomsbury, London.